腺苷脫氨酶（英語：Adenosine deaminase）的是一種參與嘌呤代謝作用的酶。它是用作拆解食物組織中的核酸中的腺苷。
反應
腺苷脫氨酶對腺苷進行不可逆轉的脫氨作用,轉化腺苷為相關的核苷肌苷,移除氨基酸組。
腺苷脫氨酶的突變基因使之不容易被表達,這是一些免疫缺陷病（ SCID ）的原因。基因突變令ADA被過度產生是溶血性貧血原因之一。有一些證據表明，一個不同的allelle (ADA2)可能會導致自閉癥。
參考文獻
深入閱讀
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1krm: Crystal structure of bovine adenosine deaminase complexed with 6-hydroxyl-1,6-dihydropurine riboside
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1ndv: Crystal Structure of Adenosine Deaminase complexed with FR117016
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1ndw: Crystal Structure of Adenosine Deaminase Complexed with FR221647
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1ndy: Crystal Structure of Adenosine Deaminase Complexed with FR230513
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1ndz: Crystal Structure of Adenosine Deaminase Complexed with FR235999
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1o5r: Crystal structure of adenosine deaminase complexed with a potent inhibitor
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1qxl: Crystal structure of Adenosine deaminase complexed with FR235380
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1uml: Crystal structure of adenosine deaminase complexed with a potent inhibitor FR233624
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1v79: Crystal structures of adenosine deaminase complexed with potent inhibitors
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1v7a: Crystal structures of adenosine deaminase complexed with potent inhibitors
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1vfl: Adenosine deaminase
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1w1i: CRYSTAL STRUCTURE OF DIPEPTIDYL PEPTIDASE IV (DPPIV OR CD26) IN COMPLEX WITH ADENOSINE DEAMINASE
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1wxy: Crystal structure of adenosine deaminase ligated with a potent inhibitor
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1wxz: Crystal structure of adenosine deaminase ligated with a potent inhibitor
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2bgn: HIV-1 TAT PROTEIN DERIVED N-TERMINAL NONAPEPTIDE TRP2-TAT (1-9) BOUND TO THE ACTIVE SITE OF DIPEPTIDYL PEPTIDASE IV (CD26)
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2e1w: Crystal structure of adenosine deaminase complexed with potent inhibitors
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